Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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CA Breast Sorlie Cluster Number 17 (60 genes) This page contains all miRNA mediated regulation and functional enrichment for CA Breast Sorlie cluster number 17. Information about breast cancer can be found on Wikipedia, and further information about the "CA Breast Sorlie" dataset can be found in Sorlie et al., 2001. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 zzz999 hsa-mir-640 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0002252 immune effector process 8 GO:0002376 immune system process 30 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 4 GO:0006513 protein monoubiquitination 4 GO:0006950 response to stress 34 GO:0006952 defense response 26 GO:0006955 immune response 26 GO:0009607 response to biotic stimulus 18 GO:0009615 response to virus 17 GO:0016032 viral reproduction 10 GO:0016574 histone ubiquitination 3 GO:0019060 intracellular transport of viral proteins in host cell 2 GO:0019221 cytokine-mediated signaling pathway 17 GO:0019882 antigen processing and presentation 5 GO:0030581 symbiont intracellular protein transport in host 2 GO:0032020 ISG15-protein conjugation 2 GO:0032606 type I interferon production 4 GO:0044419 interspecies interaction between organisms 13 GO:0046719 regulation of viral protein levels in host cell 2 GO:0048002 antigen processing and presentation of peptide antigen 4 GO:0050776 regulation of immune response 9 GO:0050789 regulation of biological process 49 GO:0050794 regulation of cellular process 44 GO:0050896 response to stimulus 40 GO:0051607 defense response to virus 6 GO:0051704 multi-organism process 28 GO:0051707 response to other organism 18 GO:0051708 intracellular protein transport in other organism involved in symbiotic interaction 2 GO:0060333 interferon-gamma-mediated signaling pathway 6 GO:0060337 type I interferon-mediated signaling pathway 16 GO:0065007 biological regulation 51 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-640 TargetScan GO:0002252 immune effector process 2 8 60 15 0.3154598 hsa-mir-640 TargetScan GO:0002376 immune system process 6 30 60 15 0.7239983 hsa-mir-640 TargetScan GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 1 4 60 15 0.2579593 hsa-mir-640 TargetScan GO:0006513 protein monoubiquitination 1 4 60 15 0.2579593 hsa-mir-640 TargetScan GO:0006950 response to stress 7 34 60 15 0.7272826 hsa-mir-640 TargetScan GO:0006952 defense response 6 26 60 15 0.4972376 hsa-mir-640 TargetScan GO:0006955 immune response 5 26 60 15 0.7242526 hsa-mir-640 TargetScan GO:0009607 response to biotic stimulus 3 18 60 15 0.7372275 hsa-mir-640 TargetScan GO:0009615 response to virus 3 17 60 15 0.6825074 hsa-mir-640 TargetScan GO:0016032 viral reproduction 2 10 60 15 0.4811828 hsa-mir-640 TargetScan GO:0016574 histone ubiquitination 1 3 60 15 0.1513735 hsa-mir-640 TargetScan GO:0019060 intracellular transport of viral proteins in host cell 0 2 60 15 0.440678 hsa-mir-640 TargetScan GO:0019221 cytokine-mediated signaling pathway 4 17 60 15 0.4251523 hsa-mir-640 TargetScan GO:0019882 antigen processing and presentation 1 5 60 15 0.367083 hsa-mir-640 TargetScan GO:0030581 symbiont intracellular protein transport in host 0 2 60 15 0.440678 hsa-mir-640 TargetScan GO:0032020 ISG15-protein conjugation 1 2 60 15 0.05932203 hsa-mir-640 TargetScan GO:0032606 type I interferon production 2 4 60 15 0.0447876 hsa-mir-640 TargetScan GO:0044419 interspecies interaction between organisms 3 13 60 15 0.4151666 hsa-mir-640 TargetScan GO:0046719 regulation of viral protein levels in host cell 0 2 60 15 0.440678 hsa-mir-640 TargetScan GO:0048002 antigen processing and presentation of peptide antigen 1 4 60 15 0.2579593 hsa-mir-640 TargetScan GO:0050776 regulation of immune response 1 9 60 15 0.7213406 hsa-mir-640 TargetScan GO:0050789 regulation of biological process 12 49 60 15 0.4407659 hsa-mir-640 TargetScan GO:0050794 regulation of cellular process 10 44 60 15 0.640448 hsa-mir-640 TargetScan GO:0050896 response to stimulus 8 40 60 15 0.829058 hsa-mir-640 TargetScan GO:0051607 defense response to virus 2 6 60 15 0.158756 hsa-mir-640 TargetScan GO:0051704 multi-organism process 5 28 60 15 0.814513 hsa-mir-640 TargetScan GO:0051707 response to other organism 3 18 60 15 0.7372275 hsa-mir-640 TargetScan GO:0051708 intracellular protein transport in other organism involved in symbiotic interaction 0 2 60 15 0.440678 hsa-mir-640 TargetScan GO:0060333 interferon-gamma-mediated signaling pathway 2 6 60 15 0.158756 hsa-mir-640 TargetScan GO:0060337 type I interferon-mediated signaling pathway 4 16 60 15 0.359552 hsa-mir-640 TargetScan GO:0065007 biological regulation 12 51 60 15 0.6009765

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